Cardi B's break is officially over, and she's got Chicago's finest -- Kanye West and Lil Durk -- for her first track since last year.

Cardi dropped "Hot S***" at midnight, and her fans are going nuts over the highly anticipated new music 

For instance ... "All this jewelry at the grocery store, I'm obnoxious / Bought a home and closin' on another, I know I'm blessed."

She even says "I don't know what's colder, man, my heart or my necklace."

Cardi was pretty hesitant about dropping the single -- she says she's been holding it for about 3 years, making it older than 2020's "WAP."

It's her first track since "Up" in 2021, and it's holding over her fans until they get that long-awaited second album. 

Cardi told followers on Instagram Live "Hot S***" doesn't have a music video, but she's confident they'll still dig it.

She thinks the song is appealing to a lot of different demographics, too -- "It's masculine, it's great for the clubs, it's great for the bitches."